Abstract. The article analyzes the effect of vibration loads in the whole body mode (WBV) on the functional state of the cardiovascular system, physical performance, activity of immune system cells, qualified athletes – canoe racing.

It was shown that there were no statistically significant changes in the main indicators of the functioning of the cardiovascular system (heart rate, blood pressure) and physical performance (PWC170) of athletes under the influence of vibration loads. The study of the blood levels of pro-inflammatory (IL-2, IL6) and anti-inflammatory (IL-4, IL-10) interleukins showed an increase IL-10 level, decrease of IL-2 level, and a lower value of the IL-6/IL-10 coefficient in athletes who trained on a vibration simulator, which indicates the predominance of anti-inflammatory processes and a decrease in the risk of developing long-term inflammation. The absence of negative effect on indicators of physical performance and the functional state of the аthletes allows us to consider WBV as an supplement of training process.

Ключові слова: whole body vibration therapy, WBV training, pro- and anti-inflammatory interleukins, physical performance, qualified athletes

Повний текст: PDF (Ukr)

1. Lage VKS, Lacerda ACR, Neves CDC, Chaves MGA, Soares AA, Lima LP, et al. Acute Effects of Whole-Body Vibration on Inflammatory Markers in People with Chronic Obstructive Pulmonary Disease: A Pilot Study. Rehabil Res Pract. 2018; 5480214.doi.org/10.1155/2018/5480214
2. Ahuja G, Arauz YLA, van Heuvelen MJG, Korholt A, Oroszi T, van der Zee EA. The effects of whole-body vibration therapy on immune and brain functioning: current insights in the underlying cellular and molecular mechanisms. Front Neurol. 2024; 15: 1422152.doi.org/10.3389/fneur.2024.1422152
3. Petrov GS, Solodka OV. Simulators in physical education and sports. Methodological recommendations for 4th year full-time and part-time students. Dnipropetrovsk (in Ukrainian)]; 2010. 39 с.
4. Wang Z, Zhang X, Sun M. The application of whole-body vibration training in knee osteoarthritis. Joint Bone Spine. 2022; 89(2): 105276.doi.org/10.1016/j.jbspin.2021.105276
5. Mukhtar M, Khan AAA, Farooq M. Effect of whole-body vibration on neuromuscular performance: a literature review. Work. 2018; 59(4): 571-583.doi.org/10.3233/WOR-182699
6. Dordevic D, Paunovic M, Cular D, Vlahovic T, Franic M, Sajkovic D, et al. Whole-Body Vibration Effects on Flexibility in Artistic Gymnastics-A Systematic Review. Medicina (Kaunas) 2022; 58(5): 595.doi.org/10.3390/medicina58050595
7. Sañudo B, Taiar R, Furness T, Bernardo-Filho M. Clinical Approaches of Whole-Body Vibration Exercises in Individuals with Stroke: A Narrative Revision Rehabil Res Pract. 2018; 8180901.doi.org/10.1155/2018/8180901
8. Ruhde L, Hulla R. An overview of the effects of whole-body vibration on individuals with cerebral palsy. J Pediatr Rehabil Med. 2022; 15(1): 193-210.doi.org/10.3233/PRM-201508
9. Ribeiro VGC, Mendonça VA, Souza ALC, Fonseca SF, Camargos ACR, Lage VKS, et al. Inflammatory biomarkers responses after acute whole body vibration in fibromyalgia. Res. 2018;l 51(4): e6775.doi.org/10.1590/1414-431x20176775
10. Adeola A, Sanni AA, Blanks AM, Derella CC, Horsager C, Crandal RH, Looney J, et al. The effects of whole-body vibration amplitude on glucose metabolism, inflammation, and skeletal muscle oxygenation. Physiol Rep. 2022; 10(5): e15208.doi.org/10.14814/phy2.15208
11. Neves CDC, Lacerda ACR, Lage VKS, Soares AA, Chaves MGA, Lima LP, et al. Whole body vibration training increases physical measures and quality of life without altering inflammatory-oxidative biomarkers in patients with moderate COPD. J Appl Physiol (1985). 2018;125(2): 520-528.doi.org/10.1152/japplphysiol.01037.2017
12. Wang Y, Ji R, Yu B. Assessing the anti-inflammatory effects of whole-body vibration:a meta-analysis based on pre-clinical and clinical evidences. Am J Clin Exp Immunol. 2024;13(3): 68-87.doi.org/10.62347/LLGY4023
13. Blanks AM, Rodriguez-Miguelez P, Looney J, Tucker MA, Jeong J, Thomas J, et al.Whole body vibration elicits differential immune and metabolic responses in obese and normal weight individuals. Brain Behav Immun Health. 2019; 1: 100011.doi.org/10.1016/j.bbih.2019.100011
14. Figueroa A, Gil R, Wong A, Hooshmand S, Park SY, Vicil F, Sanchez-Gonzalez MA. Whole-body vibration training reduces arterial stiffness, blood pressure and sympathovagal balance in young overweight/obese women. Hypertens Res. 2012; 35(6): 667-672.doi.org/10.1038/hr.2012.15
15. Jiang D, Liu С, Chen Y, Xing X, Zheng D, Guo Z, Lin S. Metabolomics Study of Wholebody Vibration on Lipid Metabolism of Skeletal Muscle in Aging Mice. Int J Sports Med. 2021; 42(5): 464-477.doi.org/10.1055/a-1268-8458
16. Jordan MJ, Norris SR, Smith DJ, Herzog W. Vibration training: an overview of the area, training consequences, and future considerations. J Strength Cond Res. 2005; 19( 2): 459-466.doi.org/10.1519/00124278-200505000-00036
17. Kalaoglu E, Bucak OF, Kokce M, Ozkan M, Cetin M, Atasoy M, et al. Whole body vibration activates the tonic vibration reflex during voluntary contraction. J Phys Ther Sci. 2023; 35(6): 408-413.doi.org/10.1589/jpts.35.408
18. Issurin VB. Vibrations and their applications in sport. A review. J Sports Med Phys Fitness. 2005; 45(3): 324-336.
19. Morel DS, da Fontoura Dionello C, Moreira-Marconi E, Brandão-Sobrinho-Neto S, Paineiras-Domingos LL, Souza P, et al. Relevance of whole body vibration exercise in sport: a short review with soccer, diver and combat sport. Afr J Tradit Complement Altern Med. 2017;14(4 Suppl.): 19-27.doi.org/10.21010/ajtcam.v14i4S.3
20. Marín PJ, Rhea MR. Effects of vibration training on muscle power: a meta-analysis.J Strength Cond Res. 2010; 24(3): 871-878.doi.org/10.1519/JSC.0b013e3181c7c6f0
21. Luo J, McNamara B, Moran K. The use of vibration training to enhance muscle strength and power. Sports Med. 2005; 35(1): 23-41.doi.org/10.2165/00007256-200535010-00003
22. Dubois DA, Dubois EF. Formula to estimate the surface area if height and weight be known. Nutrition. 1989; 5: 303-311.
23. Mihalyuk EL, Sivolap VV, Tkalich IV, Atamanyuk SI. Functional tests in sports medicine: positive and negative aspects of their implementation. Current issue in pharmacy and medicine: science and practice (in Russian)]. 2010; (23): 93-96.
24. Khoroshukha MF. The definition of physical efficience (PWC170) according to the method of power-aerometry. Scientific bulletin of South Ukrainian National Pedagogical University named after K. D. Ushynsky (in Ukrainian)]. 2018; 3(122): 102-108.
25. Torun A, Kılıç Ş, Işık Ö. Assessment Tools and Performance Development in Sports Cardiology. Int J Cardiovasc Acad. 2025; 11(1):1-5.doi.org/10.4274/ijca.2024.70288
26. Hedman K, Moneghetti KJ, Christle JW, Bagherzadeh SP, Amsallem M, Ashley E, et al. Blood pressure in athletic preparticipation evaluation and the implication for cardiac remodelling. Heart. 2019; 105: 1223-1230.doi.org/10.1136/heartjnl-2019-314815
27. Gower B, Girard D, Maiorana A, Durey B, Holland DJ, Davison K, et al. Recommendations for objective cardiovascular assessment to inform clinical exercise prescription: An Exercise Physiologist and Physiotherapist expert consensus. J Sci Med Sport. 2023; 26(9): 454-458.doi.org/10.1016/j.jsams.2023.07.004
28. Gentilin A. Identifying the Optimal Workload Combination for Maximizing Oxygen Consumption Estimation in Submaximal Tests. Movement & Sport Sciences - Science & Motricité. 2024; 125(3): 51-60.doi.org/10.1051/sm/2024013
29. Nikolaidis PT. Association between submaximal and maximal measures of aerobic power in female adolescents. Biomedical Human Kinetics. 2011; 3(1): 106-110.doi.org/10.2478/v10101-011-0023-4
30. Nieman DC, Pence BD. Exercise immunology: Future directions. J Sport Health Sci.2020; 9(5): 432-445.doi.org/10.1016/j.jshs.2019.12.003
31. Padilha CS, Figueiredo C, Minuzzi LG, Chimin P, Deminice R, Kruger K, et al. Immunometabolic responses according to physical fitness status and lifelong exercise during aging: New roads for exercise immunology. Ageing Res Rev. 2021; 68: 101341.doi.org/10.1016/j.arr.2021.101341
32. Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, et al. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011; 17: 6-63.
33. Walsh NP, Gleeson M, Pyne DB, Nieman DC, Dhabhar FS, Shephard RJ, et al. Position statement part two: maintaining immune health. Exerc. Immunol. Rev. 2011; 17: 64-103.
34. Chmielecki A, Bortnik K, Galczynski S, Kopacz K, Padula G, Jerczynska H, et al. Interleukin-4 during post-exercise recovery negatively correlates with the production of phagocyte-generated oxidants. Front Physiol. 2023; 14: 1186296.doi.org/10.3389/fphys.2023.1186296
35. Tanskanen M, Atalay M, Uusitalo A. Altered oxidative stress in overtrained athletes.J Sports Sci. 2010; 28(3): 309-317.doi.org/10.1080/02640410903473844
36. Cheng AJ, Jude B, Lanner JT. Intramuscular mechanisms of overtraining Redox Biol.2020; 35: 101480.doi.org/10.1016/j.redox.2020.101480
37. Alves MDJ, Silva DDS, Pereira EVM, Pereira DD, de Sousa Fernandes MS, Santos DFC,et al. Changes in Cytokines Concentration Following Long-Distance Running: A Systematic Review and Meta-Analysis. Front Physiol. 2022; 13: 838069.doi.org/10.3389/fphys.2022.838069
38. Kazmirchuk VE, Kovalchuk LV. Clinical Immunology and Allergology Vinnytsia: Nova Knyha (in Ukrainian)];2006. 528 с.
39. Kaya O. Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes. Biomed Rep. 2016; 5(3): 367-370.doi.org/10.3892/br.2016.730
40. Gentile A, Punziano C, Calvanese M, De Falco R, Gentile L, D'Alicandro G, et al. Evaluation of Antioxidant Defence Systems and Inflammatory Status in Basketball Elite Athletes. Genes (Basel). 2023; 14(10): 1891.doi.org/10.3390/genes14101891
41. Barbalho SM, Prado Neto EV, De Alvares Goulart R, Bechara MD, Baisi Chagas EF, Audi M, et al. Myokines: a descriptive review. J Sports Med Phys Fitness. 2020; 60(12): 1583-1590.doi.org/10.23736/S0022-4707.20.10884-3
42. Zunner BEM, Wachsmuth NB, Eckstein ML, Scherl L, Schierbauer JR, Haupt S, et al. Myokines and Resistance Training: A Narrative Review. Int J Mol Sci. 2022; 23(7): 3501.doi.org/10.3390/ijms23073501
43. Pawłowska M, Mila-Kierzenkowska C, Boraczyński T, Boraczyński M, Szewczyk-Golec K, Sutkowy P, et al. The Effect of Submaximal Exercise Followed by Short-Term Cold-Water Immersion on the Inflammatory State in Healthy Recreational Athletes: A Cross-Over Study. J Clin Med. 2021; 10(18): 4239.doi.org/10.3390/jcm10184239
44. Di Giminiani R, Rucci N, Capuano L, Ponzetti M, Aielli F, Tihanyi J. Individualized Whole-Body Vibration: Neuromuscular, Biochemical, Muscle Damage and Inflammatory Acute Responses. Dose Response. 2020; 18(2): 1559325820931262.doi.org/10.1177/1559325820931262
45. Nielsen AR, Pedersen BK. The biological roles of exercise-induced cytokines: IL-6, IL-8, and IL-15. Appl Physiol Nutr Metab. 2007; 32(5): 833-839.doi.org/10.1139/H07-054
46. Kia K, Fitch SM, Newsom SA, Kim JH. Effect of whole-body vibration exposures on physiological stresses: Mining heavy equipment applications Appl Ergon. 2020; 85: 103065.doi.org/10.1016/j.apergo.2020.103065
47. Jawed Y, Beli E, March K, Kaleth A, Loghmani MT. Whole-Body Vibration Training Increases Stem/Progenitor Cell Circulation Levels and May Attenuate Inflammation. Mil Med.2020; 185(Suppl 1): 404-412.doi.org/10.1093/milmed/usz247
48. Chen T, Liu WB, Ren X, Li YF, Li W, Hang CH, Wang YH. Whole Body Vibration Attenuates Brain Damage and Neuroinflammation Following Experimental Traumatic Brain Injury. Front Cell Dev Biol. 2022; 10: 847859.doi.org/10.3389/fcell.2022.847859
49. Juszkiewicz A, Glapa A, Basta P, Petriczko E, Żołnowski K, Machaliński B, et al. The effect of L-theanine supplementation on the immune system of athletes exposed to strenuous physical exercise. J Int Soc Sports Nutr. 2019; 16(1). 7.doi.org/10.1186/s12970-019-0274-y
50. Morel DS, Dionello CDF, Moreira-Marconi E, Brandão-Sobrinho-Neto S, Paineiras-Do-mingos LL, Souza PL, Sá-Caputo DDC, et al. Relevance of whole body vibration exercise in sport:a short review with soccer, diver and combat sport. Afr J Tradit Complement Altern Med. 2017; 14(4 Suppl): 19-27.doi.org/10.21010/ajtcam.v14i4S.3
51. Turgut E, Baltaci G. Biomechanical principles of the exercise design (Chapter 30). Іn:Comparative kinesiology of the human body. Normal and pathological condition. Editors: Angin S, Şimşek IE. Academic Pres; 2020. р. 527-538. doi.org/10.1016/B978-0-12-812162-7.00030-8
52. Cardinale M, Bosco C. The use of vibration as an exercise intervention. Sports Medicine. 2003; 33(6): 423-441.
53. Rittweger J. Vibration as an exercise modality: how it may work, and what its potential might be. Eur J Appl Physiol 2010; 108: 877-904.doi.org/10.1007/s00421-009-1303-3
54. Hortobágyi T, Lesinski M, Fernandez-Del-Olmo M, Granacher U. Small and inconsistent effects of whole body vibration on athletic performance: a systematic review and meta-analysis. Eur J Appl Physiol. 2015; 115(8): 1605-1625.doi.org/10.1007/s00421-015-3194-9
55. Games KE, Sefton JM. Whole-body vibration influences lower extremity circulatory and neurological function. Scand J Med Sci Sports. 2013; 23(4): 516-523.doi.org/10.1111/j.1600-0838.2011.01419.x
56. Tanoue T, Honda K. Induction of Treg cells in the mouse colonic mucosa: a central mechanism to maintain host-microbiota homeostasis. Semin Immunol. 2012; 24(1): 50-57.doi.org/10.1016/j.smim.2011.11.009
57. Song N, Liu X, Feng Q, Xu M, Lan X, Li M, et al. Whole Body Vibration Triggers a Change in the Mutual Shaping State of Intestinal Microbiota and Body's Immunity. Front Bioeng Biotechnol. 2019; 7: 377.doi.org/10.3389/fbioe.2019.00377