Abstract. The high frequency of prevalence and the decrease in the quality of life of patients determine the urgency of studying the peculiarities of the etiology and pathogenesis of inflammatory bowel diseases. The difficulty of finding new non-invasive markers lies in the lack of a clear understanding of the molecular mechanisms of the pathogenesis of these diseases. One of the promising directions in the diagnosis of chronic inflammatory diseases is the identification of specific miRNA molecules in blood serum, which act as powerful negative regulators of gene expression.

Article received: 19.01.2024

Keywords: Crohn’s disease, nonspecific ulcerative colitis, pathogenesis, diagnosis, miRNA

Full text: PDF (Ukr)

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